Hypothalamus PMG® for Dogs: Holistic Vet Guide to Balance & Healing

The following information is a summary and review based on Dr. Candy’s professional experience and recommendations. Any summary or statement has not been provided nor influenced by the manufacturer.

As a holistic veterinarian, I often help pet parents looking for natural ways to balance their dog’s hormones and support overall wellness. One supplement I’ve used for many years is Hypothalamus PMG® by Standard Process. This is not just another “vitamin” for dogs—it’s a targeted glandular support formula that helps keep your dog’s body in hormonal balance and healthy communication between the brain and the rest of the body.

What is Hypothalamus PMG®?

Hypothalamus PMG® is part of the Standard Process PMG (Protomorphogen) line—a collection of supplements developed to nourish and protect specific organs and glands.

The hypothalamus is a small but powerful part of your dog’s brain that helps regulate hormones, body temperature, appetite, and stress responses. When this gland is supported properly, many systems—including metabolism, thyroid, adrenal, and pituitary—work in harmony.

Key ingredients include:

  • Porcine Hypothalamus PMG™ Extract: A unique bovine glandular concentrate that provides natural cellular support for the hypothalamus.
  • Calcium Lactate: A bioavailable form of calcium that supports nerve and muscle function.
  • Magnesium Citrate: Helps regulate energy, muscle tone, and relaxation.

This combination gives the hypothalamus the nutrients it needs to function smoothly and communicate effectively with the rest of your dog’s endocrine system.

Why I Recommend Hypothalamus PMG® for Dogs

Many of the dogs I work with need help rebalancing their hormones—especially those with adrenal fatigue, thyroid issues, or chronic stress. Hypothalamus PMG® can be an important piece of that healing plan.

1. Supports Glandular and Hormonal Health

The hypothalamus acts like the “control center” for your dog’s hormones. By nourishing this gland, we help regulate things like:

  • Appetite and metabolism
  • Sleep cycles
  • Temperature regulation
  • Stress responses

2. Encourages a Stronger Immune System

When the glandular system is balanced, the immune system works more efficiently. Dogs may experience fewer seasonal flare-ups and recover faster from illness or stress.

3. Aids in Nutrient Absorption and Energy Balance

Better hormone balance improves digestion and nutrient uptake—key for energy, weight stability, and coat health.

4. Promotes Healthy Skin and Coat

Many pet parents notice shinier coats and fewer dry skin issues after adding glandular support. This is because hormones play a major role in skin repair and oil production.

5. Supports Healthy Aging

As dogs grow older, their hormone communication naturally slows. Supporting the hypothalamus can help maintain mental clarity, mobility, and vitality through the senior years.

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Key Ingredients and How They Work

Here’s a closer look at the ingredients inside Hypothalamus PMG® and how they help your dog’s body stay balanced:

IngredientHow It Helps
Porcine Hypothalamus PMG™ ExtractProvides a blueprint of healthy glandular tissue, helping the hypothalamus repair and function more efficiently.
Magnesium CitrateSupports nerve and muscle function, heart rhythm, and immune strength.
Calcium LactateStrengthens bones, assists muscle contraction, and promotes proper nerve signaling.

Each nutrient is carefully chosen to restore cellular health where the body needs it most—without synthetic hormones or harsh stimulants.

Health Conditions That May Benefit

I often include Hypothalamus PMG® in wellness plans for dogs with:

  • Endocrine imbalances such as Cushing’s or Addison’s disease
  • Thyroid or adrenal fatigue
  • Changes in appetite or metabolism
  • Temperature regulation problems
  • Behavioral changes related to stress or hormone imbalance

This supplement is not a “cure,” but it can be a valuable nutritional support within a broader holistic plan that includes diet, lifestyle changes, and (when needed) therapies like cold laser treatment to reduce inflammation and support nervous system balance.

How Hypothalamus PMG® Works

Standard Process uses Protomorphogen™ extracts, which are natural nucleoprotein-mineral compounds that help restore normal cellular communication. In simpler terms, these extracts “teach” the body how to repair and regulate itself.

By feeding the hypothalamus directly with this support, we:

  • Encourage proper hormone signaling throughout the endocrine system
  • Reduce overactivity or underactivity in hormone-producing glands
  • Support normal appetite, sleep, and mood regulation
a gray Italian Greyhound sitting attentively beside a stainless-steel food bowl filled with kibble while its owner’s hand gently places a tablet of Hypothalamus PMG into the food.

Dosage and Administration

Every dog is different, but here’s a general starting point:

Dog SizeTypical DoseFrequency
Small (1–20 lbs)1 tabletTwice daily
Medium (21–50 lbs)1½ tabletsTwice daily
Large (51+ lbs)2 tabletsTwice daily

Tips for giving Hypothalamus PMG:

  • Best given on an empty stomach for absorption.
  • Can be given directly as a chewable or hidden in a small treat.
  • Stay consistent—give at the same time daily for steady results.

If you’re unsure where to start, I can provide personalized guidance through my Online Holistic Pet Consultation service.

Possible Side Effects and Safety Notes

This supplement is generally very well tolerated. However, as with any new product:

  • Start slowly and observe your dog for any mild digestive upset (soft stool or decreased appetite).
  • If vomiting, itching, or swelling occurs, stop the supplement and contact your veterinarian.
  • Always consult your vet if your dog is pregnant, nursing, or taking prescription medications.
  • Store tablets in a cool, dry place away from sunlight.

My Holistic Recommendation

I’ve used Hypothalamus PMG® for years as part of natural hormone and metabolism support plans. When combined with high-quality whole-food nutrition and lifestyle adjustments, it helps restore balance where the body needs it most.

If your dog is showing signs of hormone imbalance—such as fatigue, mood changes, poor coat quality, or unusual appetite—this supplement may be an excellent place to start. I often pair it with nutritional support, detox formulas, or cold laser therapy for a complete, whole-body approach.

You can purchase Hypothalamus PMG® directly through Journeys Holistic Life for veterinary-approved quality and guidance.

a gray Italian Greyhound gently taking a tablet of Hypothalamus PMG from its owner’s hand like a treat

Learn More or Get Personalized Help

If you’d like a customized supplement and diet plan for your dog’s glandular or thyroid health, I offer personalized holistic consultations that include a full review of your dog’s history, nutrition, and supplement plan. You’ll receive a detailed video and written guide within two weeks of purchase.

In summary:
Hypothalamus PMG® is a gentle, natural way to support your dog’s hormone balance, energy, and overall glandular health. It’s one of my go-to tools for helping dogs feel more stable, comfortable, and vibrant at every age.


Frequently Asked Questions

What is Hypothalamus PMG® by Standard Process for Dogs?

Hypothalamus PMG® is a natural dietary supplement developed to support the health and balance of your dog’s hypothalamus gland. This small but powerful part of the brain regulates hormones, appetite, temperature, and stress responses. The formula contains porcine hypothalamus extract along with supportive minerals that help restore communication within the endocrine system for better overall wellness.

How does Hypothalamus PMG® work in dogs?

This supplement provides a unique blend of Protomorphogen™ extracts, minerals, and peptides—nutrients that directly nourish and protect hypothalamus tissue. By supporting cellular repair and normal hormone signaling, it helps your dog’s body maintain balance in areas like metabolism, energy, and stress regulation. Over time, this can improve mood, appetite, and general vitality.

How should I give Hypothalamus PMG® to my dog?

Give this supplement orally based on your dog’s size and weight, following the dosage chart above or your veterinarian’s guidance. I recommend giving Hypothalamus PMG® on an empty stomach for best absorption. Most dogs take it easily as a small treat or hidden in food.

Are there any side effects with Hypothalamus PMG®?

Hypothalamus PMG® is made from natural, food-based ingredients and is generally very well tolerated. Occasionally, a dog may experience mild digestive upset when first starting a new supplement. If you notice any unusual symptoms—such as itching, soft stool, or vomiting—pause the supplement and check with your vet. Always introduce new products gradually and monitor your dog’s response.

Can Hypothalamus PMG® be used for cats or other pets?

Yes, this supplement can also be used safely for cats and other small pets under veterinary supervision. The PMG extracts have been trusted by holistic veterinarians for decades. If you’re considering using it for another species (like reptiles or small mammals), consult your vet for dosage and safety recommendations.

Where can I buy Hypothalamus PMG?

For high-quality, veterinarian-approved supplements, you can purchase Hypothalamus PMG® directly through Journeys Holistic Life—where I personally review every product and guide pet parents in natural, holistic care.