The following information is a summary and review based on Dr. Candy’s professional experience and recommendations. Any summary or statement has not been provided nor influenced by the manufacturer.
As a holistic veterinarian, I’ve seen how much a healthy heart can impact a dog’s quality of life. Many of the dogs I work with live longer, more active lives when their cardiovascular system gets the right nutritional support. One supplement I often recommend for this purpose is Cardiotrophin PMG® by Standard Process.
This unique formula is designed to nourish and protect your dog’s heart tissue. Whether your dog is older, part of a breed prone to heart disease, or you simply want to take a proactive approach to wellness, Cardiotrophin PMG® can make a real difference.

What is Cardiotrophin PMG®?
Cardiotrophin PMG® is a whole-food-based supplement originally created for people, but veterinarians have successfully used it for dogs for decades.
The key ingredient is bovine heart PMG™ extract, a specialized nutrient derived from healthy bovine heart tissue. PMG stands for Protomorphogen™, a term coined by Dr. Royal Lee, the founder of Standard Process. Protomorphogens are unique cellular extracts that help support and maintain the healthy function of specific organs—in this case, the heart.
Since 1929, Standard Process has built a reputation for creating supplements from nutrient-dense whole foods grown on their own organic farms. Their formulas target the root of health issues instead of just managing symptoms. That’s one reason I trust their products in my own veterinary practice.
I often use Cardiotrophin PMG® as part of a holistic heart support plan, especially for dogs with heart murmurs, early congestive heart failure, or those showing fatigue and reduced stamina.
Key Benefits for Dogs
Cardiotrophin PMG® supports your dog’s heart in several important ways:
- Supports strong heart muscle cells by providing targeted nutrition to cardiac tissue.
- Encourages healthy circulation and oxygen delivery throughout the body.
- Promotes recovery after stress or illness that may affect heart performance.
- Improves overall energy and endurance, helping dogs stay playful and active.
- Supports the immune system, which is closely connected to cardiovascular health.
In my experience, this supplement can be helpful both for prevention and for dogs already dealing with mild heart challenges.

Ingredient Breakdown
Each tablet of Cardiotrophin PMG® contains a proprietary blend of 185 mg featuring:
- Bovine Heart PMG™ Extract: Provides specific nutrients that support heart tissue repair and healthy cellular function.
- Magnesium Citrate: An easily absorbed mineral that helps regulate heartbeat and supports muscle relaxation.
- Calcium Lactate: A gentle, bioavailable form of calcium important for heart rhythm, nerve signaling, and muscle contraction.
- Cellulose and Calcium Stearate: Non-active ingredients used to stabilize and preserve the tablet.
Why These Nutrients Matter
- The PMG extract delivers the nutritional blueprint for healthy heart cells.
- Magnesium helps prevent irregular heartbeats and muscle weakness.
- Calcium ensures the heart muscle contracts and relaxes efficiently.
Together, they nourish and protect the heart—one of the most energy-demanding organs in your dog’s body.
When I Recommend Cardiotrophin PMG®
I often use Cardiotrophin PMG® in my holistic treatment plans for dogs with:
- Early or mild heart disease (including murmurs or early CHF)
- Fatigue, weakness, or exercise intolerance
- Muscle weakness or loss of tone related to heart strain
- Senior dogs needing extra cardiovascular support
Because this formula works on a cellular level, it supports the body’s natural ability to maintain and repair heart tissue. It can be used alongside traditional veterinary care and other natural therapies, such as cold laser therapy, which helps improve circulation and tissue repair in the heart and surrounding muscles.

How to Give Cardiotrophin PMG® to Your Dog
The correct dose depends on your dog’s size and condition. Here’s a general guideline I use in practice:
| Dog Size | Suggested Dose |
|---|---|
| Small Dogs (1–20 lbs) | 1 tablet twice daily |
| Medium Dogs (21–50 lbs) | 2 tablets twice daily |
| Large Dogs (51+ lbs) | 3 tablets twice daily |
- For best results, give on an empty stomach so nutrients absorb more efficiently.
- If your dog has a sensitive stomach, you can give it with food—it still works very well.
- Most dogs take these tablets like treats. If yours is picky, hide the tablet in a small piece of food.
Consistency is important. Daily use provides the steady nutritional support your dog’s heart needs.
Possible Side Effects and Safety Tips
Cardiotrophin PMG® is gentle and generally well-tolerated, but every dog is different. Possible mild reactions may include:
- Temporary digestive upset (vomiting or loose stool)
- Rare allergic response (itching, swelling, or breathing changes)
If you notice any unusual symptoms, stop the supplement and contact your veterinarian.
Safety Tips:
- Always check with your vet before starting a new supplement, especially if your dog takes medications or has a medical condition.
- Follow the recommended dosage.
- Monitor your dog for any behavioral or appetite changes when first introducing the product.
This supplement is designed to support heart health, not replace a balanced diet or veterinary care.

Holistic Support for Heart Health
When I create a heart health plan for dogs, Cardiotrophin PMG® is often paired with other supportive steps:
- A fresh, whole-food diet rich in omega-3 fatty acids
- Moderate daily exercise suited to your dog’s condition
- Regular veterinary checkups, including cardiac monitoring
- Natural therapies such as cold laser therapy to improve circulation and reduce inflammation
If you’re unsure where to start, my online holistic consultation service can help you choose the right supplements and lifestyle support for your dog’s heart.
Where to Purchase
You can purchase Cardiotrophin PMG® by Standard Process directly from me through Journeys Holistic Life. I carry only veterinarian-approved products and can guide you on how to use them safely and effectively for your dog’s unique needs.
Frequently Asked Questions
Cardiotrophin PMG® is a whole-food-based supplement from Standard Process that supports your dog’s heart and circulation. It contains specific nutrients that help protect and strengthen heart tissue naturally. You can purchase Cardiotrophin PMG® for Dogs directly from me at Journeys Holistic Life.
This supplement combines bovine heart PMG™ extract, magnesium, and calcium to nourish and repair heart cells. These ingredients help maintain a steady heartbeat, support circulation, and promote healthy cardiac muscle function.
You can give the tablets directly like a treat or mix them into food. Most dogs take them easily. Follow your vet’s recommendations for dosage, or refer to the product label for weight-based guidelines.
Cardiotrophin PMG® is gentle and safe for most dogs. Occasionally, a dog may experience mild digestive upset when starting a new supplement. If that happens, pause use and check with your veterinarian.
Yes, this formula can also support heart health in cats. Always confirm dosage and suitability with your holistic veterinarian before starting any new supplement.




