As a holistic veterinarian, I’m always looking for natural ways to support your dog’s long-term health. One of my favorite nutrient combinations for overall vitality is B6-Niacinamide by Standard Process. This supplement combines two essential B vitamins that play a major role in your dog’s immune system, energy, and skin health.
Let’s take a closer look at what it does, how it works, and which dogs may benefit the most.

What Is B6-Niacinamide by Standard Process?
B6-Niacinamide combines two water-soluble B vitamins: vitamin B6 (pyridoxine) and niacinamide (vitamin B3). These nutrients support countless functions in your dog’s body, including digestion, nerve function, metabolism, and skin health.
Although this supplement was originally formulated for humans, it has been safely used by veterinarians for many years to support canine wellness.
Quick Overview
- Vitamin B6: Supports brain health, hormone balance, and metabolism of proteins and fats.
- Niacinamide (Vitamin B3): Helps maintain healthy skin, supports the nervous system, and aids in energy production.
Standard Process has been creating whole-food-based supplements since 1929, focusing on natural nutrition that supports the body’s innate healing ability.
Key Benefits of B6-Niacinamide for Dogs
B6-Niacinamide can be helpful for dogs of all ages, especially those with chronic inflammation, poor digestion, or immune challenges. Here are some of the top benefits I’ve seen in my patients:
1. Supports Immune System Function
Vitamin B6 helps produce antibodies—proteins that identify and fight bacteria and viruses. Strong immune health means fewer infections and faster recovery.
2. Promotes Healthy Skin and Coat
Niacinamide helps maintain the skin’s natural barrier, reducing dryness, itching, and irritation. Dogs with seasonal allergies or dull coats often respond well to this vitamin support.
3. Improves Nerve and Brain Function
B6 supports neurotransmitter production (the brain’s chemical messengers), which helps your dog stay alert, calm, and mentally sharp.
4. Aids Digestion and Nutrient Absorption
This supplement helps break down proteins, fats, and carbohydrates into usable energy. Better digestion means less bloating and more consistent stools.
5. Encourages Heart and Circulatory Health
B6 and B3 together help regulate cholesterol and reduce homocysteine levels, supporting healthy heart and blood vessel function.
6. Supports Pregnancy and Lactation
For breeding dogs, adequate B-vitamin levels are essential for fetal development, milk production, and maternal energy.

What’s Inside: The Key Ingredients
Each tablet of B6-Niacinamide by Standard Process includes a thoughtful combination of nutrients and food-based ingredients designed to nourish the whole body.
Primary Vitamins
- Niacin (10 mg): Converts food into energy and supports healthy skin, nerves, and digestion.
- Vitamin B6 (50 mg): Aids in brain function, hormone regulation, and metabolism.
Proprietary Whole-Food Blend (250 mg)
Includes:
- Nutritional Yeast: Natural source of B vitamins for skin and energy support.
- Bovine Liver: Rich in iron, vitamin A, and protein for healthy blood and tissue repair.
- Reishi & Shiitake Mushroom Powders: Natural immune boosters that help manage inflammation.
- Ascorbic Acid (Vitamin C): Promotes healthy joints, strong immune defense, and wound healing.
Other ingredients include pyridoxine hydrochloride (a form of B6), honey (for taste and antioxidants), calcium stearate, and arabic gum as a natural binder.
Each ingredient works together to support balanced health and healing from the inside out.
How B6-Niacinamide Supports Specific Health Issues
This supplement can be especially helpful for dogs facing certain chronic or inflammatory conditions. Here are some examples from my clinical experience:
Joint and Inflammatory Conditions (Arthritis)
Reishi and shiitake mushrooms naturally reduce inflammation, easing joint pain and stiffness.
Skin or Allergy Issues
Niacinamide strengthens the skin barrier and reduces irritation, making it a great option for dogs with hot spots, itching, or redness.
Low Energy or Anemia
The bovine liver in this formula provides natural iron and B vitamins that support red blood cell health and energy levels.
Heart and Circulatory Concerns
Niacinamide and vitamin B6 can help balance cholesterol and support circulation, particularly in older or overweight dogs.
Immune Weakness or Stress
Vitamin C and nutritional yeast help your dog’s immune system respond to stress, illness, or recovery after infection.

Dosage and Administration
Always consult your veterinarian before starting any supplement, especially if your dog is on medication or has a chronic condition.
General Dosage Guide
| Dog Size | Suggested Dosage | Frequency |
|---|---|---|
| Small (1–20 lbs) | ½ tablet | Twice daily |
| Medium (21–50 lbs) | 1 tablet | Twice daily |
| Large (51+ lbs) | 1½ tablets | Twice daily |
Crush or mix the tablet with food for easy administration. Most dogs tolerate it well when blended into a meal.
Possible Side Effects and Precautions
B6-Niacinamide is typically well tolerated, but as with any supplement, some dogs may experience mild digestive upset such as soft stool or reduced appetite.
Avoid overdose—very high doses of niacinamide can cause nausea, ulcers, or liver strain. Stick to the recommended range and check with your vet if you notice any unusual symptoms.
Safety Tips
- Always follow dosing instructions carefully.
- Monitor your dog’s behavior and digestion when introducing a new supplement.
- Store in a cool, dry place, away from pets and children.

My Holistic Approach to Vitamin Support
In my holistic practice, I often use B6-Niacinamide as part of a larger plan that includes nutrition, supplements, and cold laser therapy. Together, these tools help dogs with inflammation, fatigue, or chronic skin problems heal more completely and comfortably.
If you’d like to explore a customized supplement and nutrition plan for your dog, I offer online holistic consultations where we can create a plan tailored to your pet’s specific needs.
Where to Buy
You can purchase B6-Niacinamide by Standard Process directly through Journeys Holistic Life, where I personally select and verify each product for quality and safety.
Frequently Asked Questions
B6-Niacinamide is a natural form of vitamin B6 that supports your dog’s metabolism, helping the body convert food into usable energy. It also promotes healthy skin, coat, and nerve function. This nutrient is essential for overall vitality and is especially helpful for dogs dealing with low energy, itchy skin, or stress-related issues.
Yes, but always start under veterinary guidance. The proper dosage depends on your dog’s size, diet, and health status. In my holistic practice, I often recommend B6-Niacinamide by Standard Process as a gentle, food-based way to support metabolic and skin health. You can find it directly through Journeys Holistic Life, where I personally source trusted supplements.
Common signs of deficiency include:
– Poor growth or slow muscle development
– Dull coat or dry, flaky skin
– Low energy or fatigue
– Anemia or pale gums
– Frequent infections or weak immune response
If you notice any of these symptoms, contact your veterinarian or schedule an online holistic consultation so we can evaluate your dog’s nutritional needs.
When used correctly, it’s very safe. However, over-supplementation can cause mild digestive upset like vomiting or diarrhea. Always follow dosage instructions from your vet or from the product label. I recommend using professional-grade supplements, like those from Standard Process, to ensure purity and safety.
A well-balanced diet with fresh, high-quality ingredients provides a natural foundation. Some dogs, especially seniors or those with skin or immune issues, may benefit from added support. In those cases, I suggest using B6-Niacinamide by Standard Process, available through Journeys Holistic Life, where you’ll find only veterinarian-approved supplements.




