Ligaplex® II for Dogs: Holistic Vet Guide to Joint Health, Repair & Care

The following information is a summary and review based on Dr. Candy’s professional experience and recommendations. Any summary or statement has not been provided nor influenced by the manufacturer.

As a holistic veterinarian, I’ve seen firsthand how proper nutrition and targeted supplements can transform a dog’s health. One of my favorite products for joint and connective tissue support is Ligaplex® II by Standard Process. It’s a powerful, whole-food-based supplement that helps keep dogs strong, mobile, and comfortable—especially as they age or recover from injury.

In this guide, I’ll explain what makes Ligaplex II so effective, how I use it in my practice, and what you should know before starting it at home.

What is Ligaplex® II by Standard Process?

Ligaplex® II is a whole food supplement formulated to support connective tissue repair, joint mobility, and musculoskeletal strength in dogs.

Unlike many joint products that rely only on glucosamine or chondroitin, Ligaplex II blends vitamin-rich foods, organ extracts, and targeted minerals that nourish the body’s natural repair systems. It’s designed to work with your dog’s biology—not against it—to encourage long-term joint health.

I often recommend Ligaplex II for:

  • Dogs recovering from orthopedic injuries
  • Seniors with stiffness or reduced mobility
  • Active or working dogs who put stress on their joints
  • Breeds predisposed to joint issues like hip or elbow dysplasia

This supplement supports the body’s normal tissue repair process, which is key for healing, stability, and comfort over time.

Key Benefits of Ligaplex® II for Dogs

Ligaplex II stands out because it takes a holistic approach to your dog’s health. It doesn’t just mask symptoms—it helps strengthen the body from within.

Here are the main ways it supports your dog:

  • Joint comfort and flexibility: Helps maintain healthy cartilage and joint cushioning, reducing stiffness.
  • Connective tissue repair: Nourishes ligaments, tendons, and muscle fibers that stabilize joints.
  • Improved mobility: Keeps your dog moving comfortably—ideal for seniors or active breeds.
  • Healthy inflammatory response: Contains nutrients that support natural balance rather than over-suppression of inflammation.
  • Overall vitality: Whole-food nutrients support immune strength, energy, and recovery after exercise or injury.

Many of my clients notice small but meaningful changes—less hesitation on walks, easier transitions from lying down to standing, and a brighter, more energetic attitude.

5300-Ligaplex-ll for dogs

What’s Inside: Powerful Healing Ingredients

Ligaplex® II is built on the Standard Process philosophy of nutrient-dense, whole-food nutrition. Each ingredient is carefully selected to support the body’s repair and renewal systems.

Here’s a closer look at a few key ingredients and how they work:

  • Bovine Heart PMG™ Extract: Supports cellular repair and cardiovascular health. PMG stands for “Protomorphogen,” which are small protein compounds that help nourish tissue regeneration.
  • Veal Bone PMG™ Extract: Provides minerals and proteins that promote bone density and skeletal strength.
  • Bovine Adrenal: Helps balance the body’s stress response, supporting energy and recovery.
  • Bovine Liver: A natural source of B vitamins, iron, and amino acids for vitality and immune support.
  • Manganese Glycerophosphate: Essential for bone development and the repair of ligaments and cartilage.

These ingredients work together to strengthen connective tissue, enhance resilience, and maintain comfort throughout your dog’s life.

How Ligaplex® II Supports Specific Health Issues

Here’s how Ligaplex II can help with common concerns I see in practice:

1. Joint Discomfort and Arthritis

Ligaplex II supports cartilage regeneration and flexibility. For dogs with age-related stiffness or arthritis, it helps maintain a comfortable range of motion.

2. Ligament and Tendon Injuries

This supplement provides key minerals like manganese and vitamin C, which help rebuild and repair soft tissues—important for dogs recovering from knee injuries or sprains.

3. Musculoskeletal Weakness

For dogs that tire easily or lose muscle tone, Ligaplex II offers nutritional support for bones, muscles, and connective tissues, helping them stay strong and balanced.

4. Post-Surgical or Post-Trauma Recovery

I often use Ligaplex II as part of a rehabilitation plan after orthopedic surgery or injury, alongside cold laser therapy and a tailored nutrition plan. The combination helps reduce inflammation, accelerate healing, and restore function.

If your dog is currently recovering from an injury or surgery, I recommend scheduling an online holistic consultation so I can create a customized recovery plan that includes proper supplements, exercises, and healing therapies.

a tricolor Jack Russell Terrier lying on a wooden floor, watching attentively as its owner opens a Ligaplex II capsule and sprinkles the powder over a bowl of kibble

Dosage and How to Give Ligaplex® II

Ligaplex II is easy to give. You can offer the capsule directly or open it and mix the powder into food. Most dogs accept it readily.

General Dosage Guidelines

  • Small dogs (1–20 lbs): 1 capsule twice daily
  • Medium dogs (21–50 lbs): 2 capsules twice daily
  • Large dogs (51+ lbs): 3 capsules twice daily

These are starting doses. Once your dog’s symptoms improve, your vet may recommend reducing to a maintenance level.

Tips for Success

  • Be consistent. The best results come with daily use.
  • Pair with a fresh, whole-food diet for optimal absorption.
  • Reassess every few months with your veterinarian.

If you’re unsure where to start, I offer holistic supplement consultations where I personalize dosages and pair Ligaplex II with the right support for your dog’s unique needs.

Possible Side Effects and Safety

Ligaplex® II is very safe and well-tolerated in most dogs.

Mild side effects may include:

  • Temporary digestive upset (loose stools or mild gas)
  • Rare allergic responses such as itching or swelling

If you notice any unusual reactions, stop the supplement and contact your vet. Always start gradually and monitor your dog’s response.

Remember, supplements should complement veterinary care, not replace it. Regular checkups and lab work are still essential for long-term joint and organ health.

Holistic Vet Insight: Combining Ligaplex II With Other Therapies

For dogs with chronic joint problems, I often combine Ligaplex II with:

  • Cold Laser Therapy: Reduces inflammation and stimulates cell repair
  • Omega-3 Fatty Acids: Support anti-inflammatory balance
  • Whole-Food Diets: Promote steady energy and lean muscle
  • Musculoskeletal Support by Standard Process: For more advanced tissue repair

These combinations often help dogs regain movement faster and stay comfortable without relying solely on pain medications.

a tricolor Jack Russell Terrier gently taking a Ligaplex II capsule from its owner’s hand as if it were a treat

Where to Buy Ligaplex® II

Ligaplex® II by Standard Process is available directly through my shop at Journeys Holistic Life. Purchasing from a holistic vet source ensures you’re getting authentic products stored under proper conditions.

If you’re unsure whether Ligaplex II is right for your dog, I can help you create a personalized supplement plan based on your dog’s health, activity level, and any existing diagnoses.

Final Thoughts

Healthy joints mean a happier, more active dog. Ligaplex® II offers a safe, natural way to support those joints and keep your pet feeling young at heart. Whether your dog is a senior slowing down or an athlete recovering from strain, this supplement helps them move through life with strength and ease.

If you’d like expert guidance on which supplements fit your dog’s specific needs, schedule a Holistic Pet Consultation with me today. Together, we can design a plan that helps your dog feel their best—naturally.


Frequently Asked Questions

What is Ligaplex® II for Dogs by Standard Process?

Ligaplex® II is a whole food supplement formulated to support your dog’s joint comfort, connective tissue repair, and overall mobility. It’s made by Standard Process, a trusted company known for using nutrient-rich, food-based ingredients that work with the body’s natural healing systems.
I often recommend Ligaplex II for dogs recovering from injury, managing arthritis, or staying strong and active as they age.

How does Ligaplex® II work for dogs?

Ligaplex® II nourishes the body’s own repair mechanisms. It provides vitamins, minerals, and botanical compounds that help rebuild and protect joint structures. Key ingredients like buckwheat supply natural bioflavonoids that support circulation and strengthen blood vessels, improving oxygen and nutrient delivery to tissues.
In short, this supplement helps your dog’s body repair and maintain healthy ligaments, tendons, and cartilage—naturally.

How should I give Ligaplex® II to my dog?

The dosage depends on your dog’s size and overall health. You can open the capsule and sprinkle the powder over food or give it directly as a treat.
Refer to the dosage chart above for guidance, or schedule a holistic consultation with me if you’d like a customized supplement plan.

Are there any side effects with Ligaplex® II?

Ligaplex® II is made with natural, whole-food ingredients and is generally well tolerated by most dogs. Mild digestive changes can occur when starting any new supplement, but these typically resolve quickly.
If you notice any unusual symptoms, pause use and check in with your veterinarian.

Can Ligaplex® II be used with other medications or supplements?

Yes, Ligaplex® II can usually be safely combined with other medications or supplements. In my practice, I often pair it with Musculoskeletal Support or Omega-3 oils for enhanced joint care.
Still, it’s always best to discuss your dog’s full health plan with your vet to make sure everything works together safely.